Klein College of Science Debuts Inaugural Strategic Plan

The Klein College of Science unveiled the inaugural strategic plan “Discovering What’s Next” after an intensive, year-long process engaging feedback from stakeholders across UNC Charlotte and beyond. The plan will serve as a guide for KCOS priorities through 2032.

Founding Dean Bernadette Donovan-Merkert convened the KCOS Strategic Planning Committee on February 3, 2025, and charged it with creating an actionable roadmap — including new mission, vision and values statements — that reflect the KCOS commitment to academic excellence, societal impact and global ambitions, while aligning with UNC Charlotte’s strategic priorities.

“I am thrilled with the quality and depth of our inaugural strategic plan, which provides a bold blueprint for the future of the Klein College of Science,” said Donovan-Merkert.

Members of the KCOS Strategic Planning Committee:

  •  Kirill A. Afonin, professor of chemistry 
  • Tonya C. Bates, senior lecturer of biological sciences and 2024-25 KCOS Faculty Council chair
  • Sharon Bullock, teaching professor of biological sciences and biotechnology minor program coordinator 
  • Didier Dreau, professor of biology and graduate program pirector 
  • Jeff Gillman, director, Botanical Gardens 
  • Donald Jacobs, professor of applied physics and graduate program director
  • Reneé Johnson, office manager and assistant to the OPTI graduate program director
  • Kevin McGoff, Professor of Mathematics 
  • Rosario Porras-Aguilar, associate professor of physics and optical science
  • Juan Vivero-Escoto, professor of chemistry and director of CITRANS

The committee met weekly to collaborate, gathering input from hundreds of stakeholders through surveys, reviews of more than 50 strategic plans from leading domestic and international science colleges, and a combined SWOT and SOAR analysis.

“This plan would not have been possible without the creativity, insight and hard work of the KCOS SPC, the massive amount of thoughtful feedback to the surveys provided by stakeholders and the exemplary guidance of Dr. Sharon McDade, our Strategic Plan Consultant,” said Donovan-Merkert. “I am extremely grateful to everyone for their contributions and I look forward to working with our college, our community partners and alumni to implement the new plan and drive success for our college.”

New Nanoprinting Method with Metalenses to Speed Up 3D Fabrication and Support Large-Scale Materials Research

A team of 18 researchers has developed a high-speed method for printing precise three-dimensional (3D) structures at the nanoscale. This breakthrough could accelerate advances in microelectronics and biomedicine, and spur the development of the next generation of nanomaterials. 

The study published in Nature is a culmination of five years of work and includes research from UNC Charlotte Klein College of Science co-author You Zhou, assistant professor of physics and optical science. 

Fast and Complex

The new 3D printing system uses large arrays of “metalenses,” which are ultrathin optical devices made from nanoscale patterns, to generate more than 120,000 laser focal points at once. Each focal point acts like a tiny pen, solidifying a photosensitive resin to build precise structures, layer by layer. 

Researchers leveraged two capabilities enabled by metalenses: high-numerical aperture metalenses for sharp focusing and large arrays for high-throughput printing. The new TPL platform (two-photon lithography) prints nanoscale features in parallel to reach speeds above 120 million voxels per second, roughly 1000 times faster than conventional TPL systems. 

The arrays are paired with an ultrafast laser and a spatial light modulator that enables researchers to adjust the brightness of each focal point independently. That control allows the printer to switch individual spots on or off and fine-tune line widths to create complex 3D shapes with feature sizes down to 113 nanometers.

Overcoming Limits in Nanoscale Printing

The research addresses a major constraint that has limited TPL for decades: the small field of view of conventional microscope objectives, which restricts the printable area to only a few hundred micrometres. Scaling to larger volumes often requires stitching many smaller tiles together that can introduce “proximity effects,” where closely spaced laser spots interfere with one another. 

By eliminating the need for conventional lenses, the metalens array enables massive parallelization and turns centimeter-scale 3D printing into a single coordinated and reliable process.These advancements enabled researchers to print millions of microparticles in a day and complete tasks that previously would have required more than a month to finish in just a few hours.

Scalable Adaptive Metamaterials

Beyond speed and complex detail, the researchers used the system to fabricate large mechanical metamaterials and engineer structures with desirable properties such as high strength, low weight and programmable responses. 

Using the new TPL platform, the researchers produced three types of metamaterials:

  • Octet lattices, for stretching
  • Kelvin lattices, for bending
  • Chainmail lattices, for interlocking
The three shapes of lattices used: Octet, Kelvin and Chainmail.

The advancements to print larger sections of these patterns quickly open the door to study how the structures will deform, fracture and fail, which is key information for designing tougher and more resilient materials.

Zhou, along with researchers at Stanford University, contributed to the early design and experimental prototyping of the metalens array.

“This project is a large collaboration that was made possible by the leadership of our collaborators at Lawrence Livermore National Laboratory and Stanford University,” Zhou said. “With UNC Charlotte’s strengths in optics and its established nanofabrication infrastructure, we’re expanding our metasurface research toward a broader range of classical and nonclassical optical applications.”

Read more about the new 3D printing system in the paper published in Nature, along with a Research Highlight in Nature Electronics.

Gift from SPIE Endows $1M Scholarship Fund for Optical Science and Engineering

UNC Charlotte received a $500,000 gift from SPIE, the international society for optics and photonics. The gift was announced during the SPIE Photonics West conference held in San Francisco, California, this week. 

The gift is fully matched by a $500,000 contribution from the UNC Charlotte Foundation to form the SPIE Emerging Innovators in Optical Science and Engineering Scholarship. 

The endowment will support scholarships for two students pursuing doctoral work in UNC Charlotte’s Optical Science and Engineering program, which focuses on rapidly growing fields such as photonics, optical metrology, advanced optical materials, freeform optics, and biomedical optics. This endowed fund is the first of its kind for the Klein College of Science program.

Klein College of Science Founding Dean Bernadette Donovan-Merkert accepted the gift on stage and addressed the audience during the OPTO Plenary session. Associate Professor of Interdisciplinary Optics and Graduate Program Director Menelaos Poutous was also on hand to help accept the check. Poutous was named a Senior Member of SPIE in 2015.

“This endowment is a powerful catalyst for our growing Klein College of Science. Supporting additional doctoral students fuels the talent that will drive advances across nanophotonics, optoelectronics, freeform and biomedical optics, optical communications and more. The investment from SPIE strengthens our momentum, expands our capacity and energizes our entire Optical Science and Engineering program. We are thrilled for what this investment sets in motion.”

Bernadette Donovan-Merkert, founding dean of the Klein College of Science

The $1 million endowed fund was made possible through the SPIE Endowment Matching Program. The gift to UNC Charlotte marks the 14th major SPIE gift to universities and institutes as part of SPIE’s work supporting the international expansion of optics and photonics through increased educational capacity, funding of research and the development of talent pipelines for industry.

“Recipients of the SPIE Emerging Innovators in Optical Science and Engineering Scholarship will have an important impact on the future of optics and photonics,” said SPIE CEO Kent Rochford. “These students, pursuing their doctorates in optical science and engineering, will help contribute innovation in the field across industry, academia and government. We are delighted to work with UNC Charlotte to create these transformative opportunities for their students.”

The SPIE Endowment Matching Program was established in 2019 to increase international capacity in the teaching and research of optics and photonics. With this latest gift, SPIE has provided over $5.5 million in matching gifts as part of the program, resulting in more than $14 million in dedicated funds. The SPIE Endowment Matching Program supports optics and photonics education and the future of the industry by contributing a match of up to $500,000 per award to college, institute and university programs with optics and photonics degrees, or with other disciplines allied to the SPIE mission.

Representatives from the UNC Charlotte Klein College of Science pose with the gift from SPIE at the Photonics West Conference in San Francisco, California. L to R: Menelaos Poutous, associate professor of interdisciplinary optics; You Zhou, assistant professor of physics and optical science; Bernadette Donovan-Merkert, founding dean of the Klein College of Science; Maddie Kern, doctoral student in the Optical Science and Engineering program.

About SPIE

SPIE, the international society for optics and photonics, brings engineers, scientists, students, and business professionals together to advance light-based science and technology. The Society, founded in 1955, connects and engages with our global constituency through industry-leading conferences and exhibitions; publications of conference proceedings, books, and journals in the SPIE Digital Library; and career-building opportunities. Over the past five years, we have invested more than $26 million in the international optics community through our advocacy and support, including scholarships, educational resources, travel grants, endowed gifts, and public-policy development. www.spie.org.

About the University of North Carolina at Charlotte

More than 32,000 students choose to call North Carolina’s urban research university home. As Charlotte’s only R1 institution, UNC Charlotte drives innovation and discovery in one of the fastest-growing regions in the United States. The University has an award-winning focus on student success, internationally recognized research and creative activity, and a deep commitment to community engagement and cultural vibrancy that makes it one of U.S. News & World Report’s Top 75 Public Universities. The Difference is Charlotte. www.charlotte.edu

When Nanoparticles Learn to Talk: Building a Rosetta Stone for the Human Immune System

Researchers from the UNC Charlotte Klein College of Science discovered how to translate a new language to unlock human immunology, in the first ever study to decode microglia, the cells of the brain’s immune system.

This translator allows scientists and clinicians to compose messages in the immune system’s language by deciphering how different immune cell “dialects” generate responses. The patient’s immune system will induce a personalized response, based on the communication from tiny nucleic acid nanoparticles (NANPs), specific to their unique needs. 

Delivering the right message can save treatment time by anticipating how the immune system will react and deliver the precise response needed.

“To put it in analogy: think of the immune system as a large, diverse neighborhood of cells like monocytes, dendritic cells, macrophages or similar; each group speaks the same language with subtle dialect variations. The NANPs are like short encrypted messages defined by the nanoparticles’ size, shape and composition as well as how they are delivered.”

Kirill Afonin, team leader and professor of chemistry

The team’s earlier work studied the language of blood cells for the circulatory system. The newest study “From Sequence to Response: AI-Guided Prediction of Nucleic Acid Nanoparticles Immune Recognitions,” was published in Small, one of the leading nano and micro technology journals, and it adds a translation for the central nervous system (CNS), decoding the language of microglia.

“Microglia are part of the home security system for the CNS. These cells constantly monitor the CNS for signs of infection, inflammation, or damage. These studies are especially exciting because limiting damaging off-target effects and a lack of predictive models are major challenges for developing therapeutics for CNS disorders and diseases.”

Brittany Johnson, assistant professor of biology

The Discovery

The team’s study used a carefully prepared set of 176 unique NANPs to train a computational model. The researchers can now anticipate how the recipient cell types will respond when they open the message, and choose the appropriate response.

This newest translation is a major step toward rational immunomodulatory design. A message might:

  • Scream loudly, launching a “stranger danger” alarm that would flood the area with inflammatory signals in a cytokine storm 
  • Whisper quietly, encouraging the cells to “keep calm and carry on” and ignore the message, to keep inflammation down
  • Send a professional and measured message, asking for a moderate response in a “Goldilocks” just-right way

Instead of sending “spam” messages blindly and hoping for the best outcomes with immune response, scientists can now sketch the shape of their NANPs and run them through the AI-cell translator.

Within a few seconds, they can choose from designs that either minimize immune activation for drug delivery where stealth is needed, or maximize activation for immunotherapy where robust immune engagement is needed.

“The immune system is both a friend and a potential foe. If we don’t anticipate how it will respond, the risk of unwanted inflammation or inefficient payload delivery may endanger the therapeutic outcome.”

–Brittany Johnson

The team developed the first generation of the model, called the Artificial Immune cell or “AI-cell,” that used a library of NANPs with known physicochemical features (size, nucleic acid type, architecture, delivery vehicle) and their known immune responses, to predict how much interferon a new NANP might trigger in monocytes.

The new translation expanded the team’s previous work in several important ways:

  • Built a larger data set: To accurately predict responses from even more variations of NANPs, with distinct and wide-ranging structural and compositional differences. 
  • Upgraded the model: The transformer-based deep-learning architecture captures more complex relationships between NANP features and immune outcomes. 
  • Added a new dialect: The immune readouts now include human microglia cells, key players in addressing many CNS disorders and infections. 

“The overarching goal is to advance the AI-cell platform beyond focusing on single immune cell types and to build predictive models that capture the full ‘language’ of immune responses triggered by NANPs and interpreted across different tissues and cell types, ultimately understanding the immune responses of every system in the human body,” said Afonin.

The current AI-cell work focused on one dialect that is understood by human microglia. The further development of the AI-cell open access platform will cover multiple dialects, predicting a richer vocabulary of cytokine responses across more cell types.

This moves the field closer to “multilingual immune design” of smart NANP therapies.

Applications for the Future

Some of the broader implications for the field of therapeutic nucleic acid nanotechnology, which is a major interest of the Afonin lab, are significant:

  • Faster design cycles: Researchers can save weeks of time by running many AI-cell predictions in only seconds, prune poor designs up front and focus experimental work on the most promising NANPs.
  • Safety engineering: AI-cell offers the ability to forecast immune signatures for non-immunogenic carrier NANPs which can bring fewer surprises in later studies.
  • Tailored immunotherapies: AI-cell can tune NANPs to produce a predetermined cytokine profile for needed immune activation (e.g., cancer vaccines).
AI-Cell: NANPs technologies, Machine Learning, Immunology

“The immune system is complex, and in vitro predictions may not always map perfectly to in vivo realities: biodistribution, organ-specific responses, protein-corona formation, prior immune exposures are other factors that will influence how the immune system interprets your NANP in real life,” said Afonin. “The AI-cell tool is only as good as its training data: if certain cell types, delivery vehicles, or species are not yet tested, the predictions will be weaker in those regimes.”

In essence, the current “translator” is very good, but the conversation remains complex and needs to be constantly upgraded with additional research. Just as we might learn multiple languages to communicate with different human communities, the NANP technology learns to speak multiple “immune-dialects” so that we can engage many different monocytes, dendritic cells, or macrophages according to specific therapeutic needs.


The research reported in this publication was supported by the National Institute of General Medical Sciences of the National Institutes of Health under Award Number R35GM139587 and in part by the Intramural Research Program of the National Institutes of Health (NIH). The findings and conclusions in this publication are those of the authors and do not necessarily represent the views or policies of the NIH, the U.S. Department of Health and Human Services, or the U.S. Government. Mention of trade names, commercial products, or organizations does not imply endorsement by the U.S. Government. The work was also supported by the National Institute of Biomedical Imaging and Bioengineering of the NIH under Award Number R15EB031388 and, in part, by the Intramural/Extramural Research Program of the NCATS, NIH.

Susan Trammell discusses NCInnovation grant on Spectrum News 1

Susan Trammell, Ph.D., professor of physics and optical science, joined Spectrum News 1 to discuss how NCInnovation is helping advance her research from the lab into real-world applications.

In May 2025, Trammell received a research and development grant from NCInnovation. The nonprofit organization helps bridge the gap between academia and industry by advancing research from North Carolina public universities from proof-of-concept to commercial viability.

“They’ve been a great partner, they’ve provided funding for us to get some preliminary results so that we can go and show it to other industries,” Trammell said. “They’ve helped us develop local partnerships, so we work with some companies in Huntersville and other regional North Carolina companies to try to develop this technology.”

The grant followed a multi-month review and evaluation process led by external subject matter experts and overseen by the Program Committee of NCInnovation’s Board of Directors.

Light-Assisted Drying

Trammell and her team developed a laser technology called Light-Assisted Drying that enables medications to be stored at room temperature, expanding access worldwide.

“Every day medications like vaccines, insulin, those have to be refrigerated or frozen in some cases. That’s expensive and it limits access,” Trammell said. “The leading cause of undervaccination in children worldwide is because the areas don’t have adequate access to refrigeration, so this could have a huge impact.”

The technology, awarded U.S. Patent 11,849,722, offers a promising alternative to freeze-drying for stabilizing proteins. By eliminating the need for refrigeration during transport and storage, the technology would reduce costs by up to 80%.

“[NCInnovation] provide[s] a lot of expertise in terms of pathways to commercializing, getting that technology out of the laboratory on a campus into the real world where it can help people,” Trammell explained. “We’re academics, we’re not business people, and learning how to do that is a learning experience for us and NCInnovation is incredibly supportive with that process.”

Watch the full segment.

The Path to Pathology: Celebrating Klein College of Science Graduate Erica Flores

At the beginning of her college career, Erica Flores struggled with her confidence and belief that she deserved a “seat at the table.” 

“I think most college students can relate to the feeling of imposter syndrome, especially being a STEM major, but being part of the lab has genuinely helped me overcome this feeling,” she said.

By developing meaningful connections with professors, mentors, classmates and her fellow researchers in the Truman lab, Flores has built a network at Charlotte that has empowered her to pursue her dreams wholeheartedly, even when they are challenging.

“Reaching out for that one opportunity that you thought was impossible can actually be possible and lead to a domino effect that results in great success,” Flores said. “Of course, nothing is linear; there will be ups and downs. However, the community and mentors you encounter along the way make it all possible and worthwhile.”

Why Charlotte

Flores grew up in Apex, North Carolina, where her parents moved from Puerto Rico for a job opportunity before she was born. Inspired by her older brother who graduated from UNC Charlotte, Flores knew she wanted to follow in his footsteps and was drawn to the university’s welcoming environment, where she felt she could not only belong, but thrive.

“I truly envisioned myself being in Charlotte and having that independence away from home, but being two hours away, still close enough to feel secure,” she said. “I was attracted to Charlotte because of its diverse campus, I just thought that it was a perfect fit for me.”

From Chemistry to Biology

In 2023, Flores applied for the U.S. National Science Foundation’s Louis Stokes Alliances for Minority Participation (LSAMP) program, which offered research opportunities in STEM fields.

Erica Flores standing on a mountain with a Puerto Rican flag

Flores initially wanted to join a biology-focused lab for the program, but found that the spots filled up too quickly. She was introduced to Banita Brown, Ph.D., associate professor of chemistry and associate dean for undergraduate student affairs in the Klein College of Science, who insisted that she still join the program. Brown encouraged Flores to work in the lab of Juan Luis Vivero-Escoto, Ph.D., professor in the Department of Chemistry

“Honestly, without my participation in LSAMP, I don’t think I would have gained the experience that opened the doors for everything that has propelled me forward in my career,” said Flores. “Dr. Banita Brown was the first person that really got my foot in the door into research and was truly the catalyst for my academic and professional journey.”

Flores and Brown had only discussed the program over email during the application process, but Brown made sure to stop by Vivero-Escoto’s lab in-person to see how Flores was adjusting to the program.

“I remember feeling really nervous at the beginning of the program since it was my first real experience with professional development and my first step toward a career in STEM,” said Flores. “By the end of the summer, I was so grateful I took that opportunity. I learned the fundamentals of biology from a completely different angle and saw how they apply to major diseases like pancreatic cancer.”

“It has been an honor to know Erica and to see her advancements in research,” said Brown. “I am very proud of her accomplishments and wish her the best in her future endeavors.”

Through the LSAMP program, Flores gained foundational, hands-on experience in a research lab, which solidified her decision to pursue biology moving forward.

“I really cherished that experience,” Flores said. “But deep down, I knew I wanted to pursue something more biology-centered. Luckily, I soon received an interview offer from the Truman Lab, which became my home and my favorite place for the next two years.”

The Truman Lab members all posing for a photo in the biology lab. The group is standing in two rows, with two researchers sitting on stools in the front and holding a circular white sign with a blue bow on top. The sign has a white background and says 'Truman Lab' in colorful paint. All members are smiling at the camera.

Flores joined the Truman Lab, led by Andrew Truman, Ph.D., professor in the Department of Biological Sciences, the fall of her junior year. 

“I read some of his publications and was really interested in how his work affects cancer and different neurodegenerative diseases as well,” Flores said.

“Erica joined my lab in Fall 2023 and has since become one of our most dedicated student researchers. Working on projects ranging from purified protein systems to budding yeast, she has contributed to new insights into how proteins in different cellular compartments influence the response to heat stress,” Truman said. “Beyond her research accomplishments, Erica’s consistently positive attitude has brightened the lab environment. While we are sad to see her leave, we look forward to following her future successes!”

Flores and Chathura Pathamperuma with her research poster at the 2024 ABSGS Annual Biological Sciences Symposium
Flores and Pathamperuma at the 2024 ABSGS Annual Biological Sciences Symposium.

When Flores joined the lab, postdoctoral researcher Chathura Pathamperuma, Ph.D., became her mentor and she took on a leadership role in his project, “Understanding the Kar2 Chaperone Code.”

“What made working with him so special was that he genuinely wanted me to learn. He trusted me and after a bit of training, he stepped back and let me take the reins,” said Flores. “His style of mentoring challenged me in the best way and helped me grow exponentially as a researcher. I sincerely appreciate his trust and dedication to my learning.”

Flores continued the project by collaborating with Siddhi Omkar, Ph.D., another postdoctoral researcher in the lab.

“Siddhi is equally as remarkable,” said Flores. “She had a child not too long ago and is still committed to her work and is on the road to publication; truly superwoman behavior.”

This community has flourished due to the strong foundation of collaboration built by Truman, who truly cares about uplifting the researchers in his lab. 

“What’s special about the Truman Lab is that all members of all levels of education share that remarkable quality: talented, humble, supportive, and genuinely down-to-earth,” Flores said. “Dr. Truman is the same way. This enabled a sense of community and understanding within the lab.”

Flores feels empowered by the other researchers in the Truman Lab, where women are represented in all levels of research, from undergraduate students up to postdoctoral researchers.

“It’s mainly women within the lab, so that is super cool to see women and women of color being represented in a STEM field,” she said.

Her main advice to current and future students is to make the most of the vast research opportunities UNC Charlotte has to offer.

“If anyone has even the slightest interest in research, I would absolutely recommend they pursue it. UNC Charlotte offers such great opportunities for students, and all students should make the most of them,” Flores said.

Ashley Choi, Shreya Patel, and Erica Flores taking a selfie at the SACNAS conference.
Truman Lab members Ashley Choi (left), Shreya Patel (middle) and Erica Flores (right).
The Fine9 dance crew taking their final performance bows

In addition to her impressive academic achievements and research in the lab, Flores enjoys expressing herself through her Korean Pop (K-pop) dance groups. She is a member of the on-campus Fine9 K-pop Dance Club as well as a local, independent K-pop dance group called FAN-C Dance Crew.

Both groups post K-Pop dance covers on their social media accounts and perform live dance routines at festivals and showcases, building confidence, creativity and teamwork through the synchronized choreography to popular songs.

On Sunday, Nov. 23 in McKnight Hall, Fine9 held their Winter Showcase. Flores participated in several dances, including XOXZ by IVE, Jellyous by ILLIT, Come Over by LE SSERAFIM, LA DI DA by Everglow, RUN2U by STAYC, and Body by MEOVV.

“I love Korean culture and dance in general. I did dance growing up, so I just love expressing myself through dance and also just physically exerting myself,” Flores said.

Erica Flores on stage for the Fine9 performance of Jellyous
Performing Jellyous by ILLIT.
Erica Flores and three other dancers performing on stage
Performing Come Over by LE SSERAFIM.
Fine9 dance crew seniors pose on stage
Celebrating the seniors in Fine9.
Erica Flores and Shreya Patel posing with their awards from the 2024 ABSGS Annual Biological Sciences Symposium
In October 2024, Flores received the 3rd Place Undergraduate Student Poster award at the Association of Biological Sciences Graduate Students (ABSGS) Annual Biological Sciences Symposium.

Communicating Science

Flores has taken the skills she has learned from her great mentors and utilizes them to help other students develop their own research skills.

As a communications consultant for the Cell Biology Lab, taught by Michelle Pass, Ph.D., Flores helps students learn how to communicate their lab work effectively. Flores joins the course every other week to give a presentation on how to write lab papers, focusing on topics such as the materials and methods section.

“I really like the job because I feel like writing for me is a pretty daunting task because it can take a while to refine and can be overwhelming if it’s a long paper,” Flores explained. “So being able to help other students is really fulfilling.”

Flores has expanded her own skills in research communication through attending conferences and presenting her work.

SACNAS

In 2023, Flores joined the Society for Advancement of Chicanos/Hispanics & Native Americans in Science (SACNAS), a student organization, after encouragement from Ashley Choi. Choi joined the Truman lab in 2022 and graduated last year.

Flores took on the role of vice president in the fall of 2024 and was awarded the 2024 SACNAS NDiSTEM COLOR Travel Scholarship. The scholarship funded her travel and attendance for the NDiSTEM Conference in Phoenix, Arizona in October 2024, with over 5,500 other attendees ranging from college-level to professionals in the field. 

As the leading multidisciplinary and multicultural STEM conference in the country, SACNAS NDiSTEM immerses attendees in cutting-edge research, professional development sessions, an academic and career exposition and multicultural celebrations and traditions.

“Having the opportunity to present at a conference, that’s also a diverse conference, and seeing people that look like me explaining their research is really empowering,” Flores said. “It gives me the confidence to pursue my career in STEM.”

Future Plans

Erica Flores posing with her green graduation cap and gown

Flores is graduating this December with a major in biological sciences and a minor in public health.

In January 2026, Flores will start the Histotechnology Program led by Carolinas College of Health Science, part of Atrium Health. The 31-week program teaches students the skills for work in research and hospital settings, training students to pass the Histotechnology Certification.

After obtaining the certification, Flores is interested in pursuing a pathologists’ assistant training program. Pathologists’ assistants spend two years taking medical school level courses and completing practical rotations in order to provide surgical pathology and autopsy pathology services under the direct supervision of a board certified pathologist.

“There are only a couple programs in the United States, but there’s one at Duke,” Flores said. “I know it will be hard, but I think if I really commit that it could be a possibility.”

Her interest in pathology was solidified by how much she enjoys hands-on lab work and the satisfaction of understanding how things function at the structural and diagnostic levels. 

“I liked the investigation of how things work the way they do and how we can apply that to the human body to make a real impact on people,” Flores said. “I found that pathology really blends patient care, lab work and investigation in a way that feels truly fulfilling.”

Flores knows that stepping away from the daily routine in the lab will be the most difficult part of graduating and leaving UNC Charlotte.

The lab has given her incredible opportunities to collaborate on groundbreaking discoveries and present at exciting conferences, but she will miss the daily interactions with her fellow researchers and friends more than anything else.

“I think what I’ll miss most are our weekly lab meetings. Each lab member takes a turn presenting their hard work and the status of their research. This way, we get to see how our projects overlap and help each other move forward with our research,” she explained. “Those small moments are what made the lab feel like a true community.”

Truman Lab group photo with all members smiling at the camera and doing the UNC Charlotte pickaxe with one hand
The Truman Lab in 2024. From left to right, Seated: Siddhi Omkar and Duhita Mirikar Middle: Erica Flores, Andrew Truman, Ph.D., Ashley Choi, Yevheniia Bushman, Ph.D., Shreya Patel, Megan Mitchem, and Rajlekha Deb Back: Chathura Paththamperuma, Ph.D., Nick Maynard, and Ishaan Koradia.

Truman Lab photos by Amy Hart.
Additional images courtesy of Erica Flores.

Poler Team Passes Industry-Standard Filtration Certifications, Allowing Commercial Production on Water Filters

Patented nanomaterial technology developed at UNC Charlotte could soon improve the quality of drinking water. 

Jordan Poler, Ph.D., has successfully passed filtration testing with his water purification system, paving the way for large-scale production on filters that remove forever chemicals and other contaminants from water.

Poler, a professor of chemistry in the UNC Charlotte Klein College of Science, is a leader in advanced water purification solutions, using a patented nanostructured filtration media developed by his team at the University.

The filters passed NSF/ANSI 42 and 61 Point-of-Use (POU) testing, which are industry-standard certifications that confirm the filters are both safe and effective for drinking water treatment. 

The technology, developed through years of research in nanomaterials and membrane science, provides a new approach to removing contaminants from drinking water. Unlike conventional filtration media, the materials developed by the Poler team feature an engineered nanostructure that enhances selectivity and capacity while maintaining sustainability and lowering regeneration costs.

This important validation was made possible through support from the NCInnovation, which invests in North Carolina-based technologies with high commercial potential. 

A blue golved hand holds a clear glass beaker full of small tan particles.

Goulston Technologies of Monroe, North Carolina, is an established specialty chemical manufacturer that is partnering with Poler’s nanXPure to scale up production with full manufactured certification, using industry-ready methods. Once manufacturing certification is complete, nanXPure will lead commercialization efforts from its headquarters in Huntersville, North Carolina, bringing a new generation of safe, efficient and sustainable purification filters to the global water treatment market.

“This milestone confirms that our materials meet the highest standards for safety and performance,” said Poler. “With the continued support of NCInnovation and our partners at Goulston Technologies, we’re positioned to deliver real-world solutions to one of the most pressing challenges of our time — access to clean water.”

To date, NCInnovation has awarded $18.8 million in funding across 25 projects statewide, 14 UNC System schools and multiple industries. In the Klein College, Pinku Mukherjee and Susan Trammell were awarded NCInnovation grants earlier this year. A new slate of awards will be announced in December 2025.

Nobel Laureate Visits UNC Charlotte to Celebrate 20 Years of ‘Remarkable’ Mathematical Finance Program

UNC Charlotte recognized 20 years of the nationally-ranked Mathematical Finance program with Nobel laureate Robert C. Merton helping to mark the occasion.

“I want to commend the remarkable achievement of the Mathematical Finance program,” Merton told the audience of 225+ at The Dubois Center at UNC Charlotte Center City. “I say remarkable not lightly. Establishing in less than one-quarter of a century the rankings, the development and the support that you have in this program may look easy to those who don’t know, but it’s a very difficult thing to do from scratch. You should take great pride and pleasure in this.”

The program was born two decades ago with support particularly from Bank of America and Wachovia, which later integrated into Wells Fargo. Cultivating corporate involvement and adapting curriculum to emerging needs have been essential to ensuring the program delivers the talent Charlotte needs, said Belk College of Business Dean Richard Buttimer.

“Our program’s interdisciplinary core has been critical to its versatility and its responsiveness,” Buttimer said. “The collective knowledge we have in economics, finance and mathematics and statistics in the Belk College and in the Klein College of Science continues to prepare our graduates to thrive in the rapidly evolving quantitative world.”

The emphasis of the two colleges on excellence in academics, research and engagement with employers has advanced the vitality of the Charlotte region, particularly in the nation’s second largest financial and banking center.

“The Klein College of Science and our Mathematics and Statistics Department are focused on shaping the future of scientific discovery,” said college Founding Dean Bernadette Donovan-Merkert. “We cultivate a spirit of inquiry that our graduates take into their careers, many of them in Charlotte.”

Attendees at the celebration tapped into their own spirits of inquiry, as Merton — a founder of modern finance and risk management — discussed a growing global and local challenge. Households today hold greater responsibility than in the past for decisions about retirement funding and associated risks. Yet, they often don’t have the knowledge or tools they need, Merton said. People and organizations need to shift their thinking and their approaches, he said.

Nobel laureate Robert C. Merton, Klein College of Science Founding Dean Bernadette Donovan-Merkert, Mathematics and Statistics Department Chair Taufiquar Khan.

Jordan Poler awarded 2025 ‘Best Scientist’ by Queen City Nerve

Jordan Poler, Ph.D., professor in the Department of Chemistry, is the winner of the “Best Scientist” category of Queen City Nerve Critics’ Pick Winners: Best in the Nest 2025 list. 

Poler has been recognized as a leader in advanced water purification solutions. At UNC Charlotte, his research group focuses on nanomaterials and membrane science, and they have developed a new approach to removing harmful contaminants from drinking water. 

Conventional filters in water pitchers or under-sink systems may remove toxins such as perfluoroalkyl and polyfluoroalkyl substances (PFAS), or “forever chemicals,” from drinking water, but once they are tossed in a landfill the chemicals leach back into the environment.

Poler’s non-toxic materials can be packed into water filtration cartridges and used to remove pharmaceuticals, pesticides, arsenates, heavy metals and PFAS at the point of use, such as a tap water filter in the refrigerator.

Unlike refrigerator filters that must be replaced regularly, Poler’s materials can be regenerated and reused. He plans for customers to ship their used cartridges back in provided mailers, cutting down on plastic waste and keeping the PFAS and other toxins from reentering the environment.

Poler’s startup, nanXPure LLC, has partnered with a specialty chemical manufacturer, Goulston Technologies in Monroe, NC, to bring the filtration technology to industry scale.

The Poler Research Group at UNC Charlotte receives support from the NCInnovation Fund, which helps facilitate the commercialization of applied research from North Carolina universities. 

Check out the full list of winners here.

Read Poler’s feature in the Coastal Review to learn more about his research.

Foley Lab research article selected for journal cover pays tribute to The Beach Boys

A research article by the Foley Lab in the Klein College of Science has been selected as a cover of the Journal of Chemical Theory and Computation.

Research for the article, Modeling Strong Light-Matter Coupling in Correlated Systems: State-Averaged Cavity Quantum Electrodynamics Complete Active Space Self-Consistent Field Theory, was led by postdoctoral researcher Nam Vu and graduate student Kenny Ampoh under the direction of principal investigator Jay Foley, associate professor in the Department of Chemistry.

Both the cover graphic and the table of contents (TOC) figure in the abstract pay tribute to one of Foley’s creative heroes, Brian Wilson, the visionary songwriter and musical genius behind The Beach Boys.

The journal cover references “Surf’s Up” written by Wilson and Van Dyke Parks, while the TOC figure draws inspiration from the more widely known “Good Vibrations.” 

“Being selected for the journal cover allows us to share what we find beautiful about quantum phenomena with a broader audience,” said Foley. “Brian Wilson passed away during this project, and the song “Surf’s Up” became a daily companion as I reflected on the impact his music has had on me. Over time, I started building associations between the poetic imagery of the song and the quantum phenomena we are working on.”

The cover image transforms the imagery from the song’s lyrics into a scientific metaphor, with the molecular and harmonic potentials becoming the “pit and pendulum drawn” through opera glasses.

A “quicksilver moon” brightens the quantum landscape above a beach scene featuring palm trees and a surfboard, while a record player plays “Surf’s Up!” below.

“Wilson spoke about his mission to explore beauty and joy through music, which resonates with me personally; I’m more animated scientifically by ideas that I find beautiful or mysterious than by potential utility,” said Foley. 

The Foley Lab works to further understand interactions between light and matter. For this research, they worked alongside Mikuláš Matouseǩ and Libor Veis at the J. Heyrovský Institute of Physical Chemistry, part of the Academy of Sciences of the Czech Republic, and Niranjan Govind from the Pacific Northwest National Laboratory.

“There is growing evidence that suggests that ‘strong’ interactions between light and molecules, which is achieved by confining them in nanoscale structures, can enable new chemical reactions and provide unprecedented control over molecular processes,” said Vu. “These structures concentrate light’s energy into extremely small volumes, making quantum features of light as striking as those of molecules, including vacuum fluctuations that can exert significant forces even in complete darkness.”

Image from the journal cover. A "quicksilver moon" brightens the quantum landscape above a beach scene featuring water, sand, palm trees and a surfboard, while a record player plays “Surf’s Up!” below. Large opera glasses in the middle of the scene have a trapped molecule between the mirrored lenses.
The opera glasses in the cover image are styled as Fabry–Pérot cavities, including a trapped molecule between the mirrored surfaces.
The TOC graphic referencing "Good Vibrations," which shows the fundamental vibrations of the molecule changing as a result of the excitations from the confined light from above.
The TOC graphic references “Good Vibrations,” with the fundamental vibrations of the molecule changed as a result of the excitations from the confined light from above.

The interactions create quantum states called ‘polaritons,’ which are exotic hybrid entities of neither purely light nor purely matter. Experiments have shown that polaritons can make desired reactions proceed faster or steer them toward specific products. The “Good Vibrations” TOC graphic gives a nod to this process where the confined light gives molecules excitations, and the fundamental vibrations of the molecule are changed as a result.

“Our theoretical research helps understand these quantum phenomena and provides insights that experimentalists and engineers can use to design practical setups, potentially transforming the chemistry lab of the future to include specialized optical cavities alongside traditional equipment,” said Ampoh.


The Foley Lab wishes to gratefully acknowledge the support of the U.S. Department of Energy, the Department of Chemistry, and the Center for Innovation, Translational Research and Applications of Nanostructured Systems (CITRANS), which made this work possible. 

Images courtesy of the Foley Lab.